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While no substantial discrepancies had been present in tyrosine hydroxylase exercise and expression, Mind tissue amounts of 3,4-dihydroxyphenylalanine were being threefold greater in α2A- and α2C-adrenoceptor KO mice. Mind tissue amounts of dopamine and noradrenaline were being drastically higher in α2A and α2CKOs compared with WT [WT: two.M, a